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Genfit SA (GNFT.PA)

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4,2960+0,0200 (+0,47 %)
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Var. jour4,2300 - 4,3300
Sur 52 semaines3,0220 - 20,9600
Volume436 678
Volume moyen706 910
Cap. boursière166,685M
Bêta (mensuel sur 5 ans)1,18
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BPA (sur 12 mois)S.O.
Date de bénéficesS.O.
Dividende et rendement à termeS.O. (S.O.)
Date ex-dividendeS.O.
Objectif sur 1 anS.O.
  • Globe Newswire

    GENFIT: Revenues and Cash Position as of December 31, 2020

    Cash and cash equivalents totaled €171 million as of December 31, 2020The announced cash position omits the partial buyback of the OCEANEs convertible bonds by GENFIT, for €47.48 million1, completed in January 2021 Lille, France; Cambridge, MA; February 26, 2021 - GENFIT (Nasdaq and Euronext: GNFT), a late-stage biopharmaceutical company dedicated to improving the lives of patients with metabolic and liver diseases, today announced its cash position as of December 31, 2020 and revenues for 20202. Financials As of December 31, 2020, the Company’s cash and cash equivalents amounted to €171.0 million compared with €276.7 million, as of December 31, 2019. As of June 30, 2020, cash and cash equivalents amounted to €225.7 million. The cash position as of December 31, 2020 omits the cost of the partial buyback by the Company for its convertible bonds (OCEANEs) issued in October 2017 and amounting to approximately €180 million. Following the completion of this transaction, €85.7 million of convertible debt was canceled by spending a gross amount of only €47.48 million. Given the conversions of bonds into shares in January 2021, which led to the creation of 3,037,309 new shares in February 2021, the residual convertible debt, initially reduced to a nominal amount of €94.3 million through the partial buyback transaction, was further reduced by a nominal amount of €16.3 million, with approximately €78 million outstanding as of February 18, 2021. Pascal Prigent, CEO of GENFIT, commented: “Since the announcement of our new corporate strategy in the Fall of 2020, GENFIT has achieved a significant amount and I’m satisfied with the early direction of 2021. ELATIVETM, our Phase 3 clinical trial in PBC, is on track, and we recently organized a KOL event on this disease, which highlighted the potential of elafibranor in this market already worth >$300M in 2020, and expected to reach $1bn in 2025, at the time we hope to launch. Next to this, we successfully restructured the convertible debt at the end of January 2021, with a maturity extended to October 2025. Some bondholders have since converted their OCEANEs, further reducing the outstanding debt to approximately €78 million. We will present advances on our R&D programs at the next corporate update, to take place before the summer.” Revenues 3 Revenues for 2020 amounted to €765 thousand compared to €31 million for 2019. Revenues included revenues from the licensing agreements with Covance/Labcorp to roll out the NIS4™ diagnostic technology in NASH and the sale of goods and services provided pursuant to the collaboration and license agreement with Terns Pharmaceuticals. As a comparison, revenues for 2019 mainly consisted of the $35 million upfront payment received from Terns Pharmaceuticals as part of the collaboration and license agreement. Reminder On September 30, 2020, GENFIT announced its plan to reduce its cash burn by 50% by 2022 compared to the cash burn before the publication of the RESOLVE-IT Phase 3 data readout. The Company reiterates its goal to reduce the cash burn rate from €110 million annually before our Phase 3 data, to approximately €45 million annually, beginning in 2022. 2021 will be a transition year with a cash burn of approximately €75 million (excluding the partial OCEANEs buyback transaction for €47.48 million in cash) mainly due to the residual expenses related to the termination of the RESOLVE-IT clinical trial, and to costs associated with the workforce reduction plan. Upcoming Financial Communications The Company will release its full-year 2020 financial results on April 1, 2021. The 2020 Universal Registration Document, the 2021 Annual Financial Report (included in the 2020 Universal Registration Document), and the Annual Report on Form 20-F will be published by the end of April 2021. ABOUT GENFIT GENFIT is a late-stage biopharmaceutical company dedicated to improving the lives of patients with cholestatic and metabolic chronic liver diseases. GENFIT is a pioneer in the field of nuclear receptor-based drug discovery, with a rich history and strong scientific heritage spanning more than two decades. GENFIT is currently enrolling in ELATIVE™, a Phase 3 clinical trial evaluating elafibranor in patients with Primary Biliary Cholangitis (PBC). Elafibranor is an investigational compound that has not been reviewed and has not received approval by any regulatory authority. As part of GENFIT’s comprehensive approach to clinical management of patients with liver disease, the Company is also developing NIS4™, a new, non-invasive blood-based diagnostic technology which could enable easier identification of patients with at-risk NASH. NIS4™ technology has been licensed to LabCorp® in the U.S. and Canada for the development and commercialization of a blood-based molecular diagnostic test powered by NIS4™ technology. GENFIT has facilities in Lille and Paris, France, and Cambridge, MA, USA. GENFIT is a publicly traded company listed on the Nasdaq Global Select Market and on compartment B of Euronext’s regulated market in Paris (Nasdaq and Euronext: GNFT). www.genfit.com FORWARD LOOKING STATEMENTS This press release contains certain forward-looking statements with respect to GENFIT, including those within the meaning of the Private Securities Litigation Reform Act of 1995, with respect to GENFIT, including statements regarding the Company’s ability to meet clinical, regulatory and commercial milestones and timelines in our PBC program, expectations for disease prevalence, growth and size of the PBC market, including GENFIT’s potential market share and revenues and projected cash burn. The use of certain words, including “consider”, “contemplate”, “think”, “aim”, “expect”, “understand”, “should”, “aspire”, “estimate”, “believe”, “wish”, “may”, “could”, “allow”, “seek”, “encourage” or “have confidence” or (as the case may be) the negative forms of such terms or any other variant of such terms or other terms similar to them in meaning is intended to identify forward-looking statements. Although the Company believes its projections are based on reasonable expectations and assumptions of the Company’s management, these forward-looking statements are subject to numerous known and unknown risks and uncertainties, which could cause actual results to differ materially from those expressed in, or implied or projected by, the forward-looking statements. These risks and uncertainties include, among other things, the uncertainties inherent in research and development, including in relation to safety, biomarkers, progression of, and results from, its ongoing and planned clinical trials, review and approvals by regulatory authorities of its drug and diagnostic candidates, exchange rate fluctuations and the Company’s continued ability to raise capital to fund its development, as well as those risks and uncertainties discussed or identified in the Company’s public filings with the AMF, including those listed in Chapter 2 “Main Risks and Uncertainties” of the Company’s 2019 Universal Registration Document filed with the AMF on 27 May 2020 under n° D.20-0503 and in Section 2 “Risk Factors” of the Company’s Amendment to the Universal Registration Document filed with the AMF on 22 December 2020 under n° D.20-0503-A01, which are available on the Company’s website (www.genfit.com) and on the website of the AMF (www.amf-france.org) and public filings and reports filed with the U.S. Securities and Exchange Commission (“SEC”) including the Company’s 2019 Annual Report on Form 20-F filed with the SEC on May 27, 2020. In addition, even if the Company’s results, performance, financial condition and liquidity, and the development of the industry in which it operates are consistent with such forward-looking statements, they may not be predictive of results or developments in future periods. These forward-looking statements speak only as of the date of publication of this document. Other than as required by applicable law, the Company does not undertake any obligation to update or revise any forward-looking information or statements, whether as a result of new information, future events or otherwise. CONTACT GENFIT | Investors Naomi EICHENBAUM – Investor Relations | Tel: +1 (617) 714 5252 | investors@genfit.com PRESS RELATIONS | Media Hélène LAVIN – Press relations | Tel: +333 2016 4000 | helene.lavin@genfit.com 1 Excluding transaction-related costs 2 Unaudited financial information under IFRS3 Revenues recognized under IFRS 15 GENFIT | 885 Avenue Eugène Avinée, 59120 Loos - FRANCE | +333 2016 4000 | www.genfit.com Attachment GENFIT: Revenues and Cash Position as of December 31, 2020

  • Globe Newswire

    GENFIT : Chiffres d’Affaires et Position de Trésorerie au 31 décembre 2020

    Trésorerie et équivalents de trésorerie s’élèvent à 171 millions d’euros au 31 décembre 2020Cette position ne tient pas compte de l’opération de rachat d’une partie de ses OCEANEs réalisée en janvier 2021 dans laquelle la Société a engagé un montant de 47,48 millions d’euros1 Lille (France), Cambridge (Massachusetts, États-Unis), le 26 février 2021 – GENFIT (Nasdaq et Euronext: GNFT), société biopharmaceutique de phase avancée engagée dans l’amélioration de la vie des patients atteints de maladies hépatiques et métaboliques, annonce aujourd’hui la position de sa trésorerie au 31 décembre 2020 et son chiffre d’affaires pour l’année 20202. Situation de Trésorerie Au 31 décembre 2020, la trésorerie et les équivalents de trésorerie de la Société s’élevaient à 171,0 millions d’euros contre 276,7 millions d’euros au 31 décembre 2019. Au 30 juin 2020, la trésorerie et les équivalents de trésorerie totalisaient 225,7 millions d’euros. Cette position de trésorerie au 31 décembre 2020 ne tient pas compte de l’opération réalisée au mois de janvier 2021 par la Société de rachat d’une partie des obligations convertibles en actions (OCEANES) émises en octobre 2017 pour un montant nominal d’environ 180 millions d’euros ; opération à l’issue de laquelle, 85,7 millions d’euros de dettes convertibles ont été effacés en ne mobilisant qu’un montant de trésorerie de 47,48 millions d’euros dans la transaction. Compte tenu des conversions en actions des OCEANEs intervenues au titre du mois de janvier 2021, qui ont donné lieu à la création de 3 037 309 actions nouvelles au mois de février 2021, la dette convertible résiduelle, une première fois réduite pour s’établir à un montant nominal de 94,3 millions d’euros grâce à cette opération de rachat partiel, s’est à nouveau réduite d’un montant nominal de 16,3 millions d’euros pour s’établir désormais à environ 78 millions d’euros au 18 février 2021. Pascal Prigent, Directeur Général de GENFIT, a commenté : « Depuis l’annonce de notre nouvelle stratégie à l’automne 2020, GENFIT a accompli beaucoup de choses et je suis très satisfait de la direction prise en ce début d’année 2021. Notre étude de Phase 3 dans la PBC, ELATIVETM, se poursuit comme prévu et nous venons d’organiser un KOL event sur cette pathologie, qui a mis en évidence le potentiel d’elafibranor sur ce marché représentant déjà plus de 300 millions de dollars en 2020, et qui devrait atteindre 1 milliard de dollars en 2025, au moment où nous espérons pouvoir lancer. Par ailleurs, nous avons restructuré la dette convertible avec succès, fin janvier 2021, avec notamment une maturité repoussée à octobre 2025. Depuis, des porteurs d’obligations ont converti leurs OCEANES, réduisant encore la dette résiduelle qui s’établit désormais à environ 78 millions d’euros. Nous vous présenterons les avancées de nos programmes R&D lors d’un point d‘étape que nous organiserons d’ici l’été. » Chiffre d’affaires3 Le chiffre d’affaires de 2020 s’élève à 765 milliers d’euros contre 31 millions d’euros réalisé au titre de l’exercice 2019. Dans ce chiffre d’affaires figurent notamment les revenus réalisés dans le cadre des contrats de licence avec Covance/Labcorp pour le déploiement de la technologie de diagnostic NIS4™ dans le domaine de la NASH, et ceux résultant de la vente de biens et de services réalisés notamment dans le cadre du contrat de licence et de collaboration avec Terns Pharmaceuticals. En comparaison, le chiffre d’affaires de l’année 2019 contenait essentiellement un paiement initial d’un montant de 35 millions de dollars, perçu à l’occasion de la signature du contrat de licence et de collaboration avec Terns Pharmaceuticals. Rappel Le 30 septembre 2020, GENFIT a annoncé son objectif de réduire de plus de 50% son rythme de consommation de trésorerie d’ici 2022 par rapport à ce qu’il était avant les résultats de la phase 3 RESOLVE-IT. La Société réitère son objectif consistant ainsi à passer d’un rythme de plus de 110 millions par an avant les résultats de la phase 3 RESOLVE-IT à une consommation de l'ordre de 45 millions en 2022. L’année 2021 devrait être une année de transition en matière de consommation de trésorerie d’exploitation, de l’ordre de 75 millions d’euros (hors opération de rachat partiel des OCEANEs ayant mobilisé un montant de trésorerie de 47,48 millions d’euros4) principalement en raison du reliquat des dépenses et des sommes restant à décaisser liées aux opérations de clôture de RESOLVE-IT, ainsi que des coûts accompagnant le plan de réduction des effectifs. Prochaines communications financières La Société publiera ses résultats annuels 2020 complets le 1er Avril 2021. Le Document d’Enregistrement Universel 2020 et son Rapport Financier Annuel 2020 (inclus dans le Document d’Enregistrement Universel 2020) et le Rapport Annuel de Form 20-F seront rendus publics d’ici la fin du mois d’Avril 2021. À PROPOS DE GENFIT GENFIT est une société biopharmaceutique avancée engagée dans l’amélioration de la vie des patients atteints de maladies cholestatiques et métaboliques chroniques du foie. GENFIT est pionnier dans le domaine de la découverte de médicaments basés sur les récepteurs nucléaires, fort d'une histoire riche et d'un solide héritage scientifique de près de deux décennies. GENFIT recrute actuellement des patients pour ELATIVE™, un essai clinique de Phase 3 évaluant elafibranor dans la cholangite biliaire primitive (« PBC »). Elafibranor est un composé en cours d’évaluation et n’a été revu ni n’a reçu d’approbation d’aucune autorité réglementaire. Abordant la prise en charge clinique des patients atteints de maladies hépatiques à travers une approche intégrée, GENFIT développe également NIS4™, une technologie nouvelle de diagnostic visant à faciliter l’identification des patients atteints de NASH « à risque ». NIS4™ fait l’objet d’un accord de licence à la Société LabCorp® pour le développement et la commercialisation aux Etats-Unis et au Canada d’un test diagnostic moléculaire sanguin basé sur cette technologie. GENFIT est installée à Lille, Paris et Cambridge, MA (États-Unis). GENFIT est une société cotée sur le Nasdaq Global Select Market et sur le marché réglementé d’Euronext à Paris, Compartiment B (Nasdaq et Euronext : GNFT). www.genfit.fr AVERTISSEMENT Ce communiqué de presse contient des déclarations prospectives à propos de GENFIT, y compris au sens où l’entend le Private Securities Litigation Reform Act de 1995 et en particulier des déclarations prospectives relatives à l’atteinte d’étapes cliniques, réglementaires et commerciales de notre programme dans la PBC, aux projections sur la prévalence de la maladie, sur la taille et la croissance du marché de la PBC, dont la part de marché et revenus potentiels de GENFIT et prévisions de consommation de trésorerie de la Société. L’utilisation de certains mots, comme tels que « considérer », « envisager », « penser », « avoir pour objectif », « s’attendre à », « entendre », « devoir », « ambitionner », « estimer », « croire », « souhaiter », « pouvoir », « permettre », « viser », « encourager », « être confiant » ou, le cas échéant, la forme négative de ces mêmes termes, ou toute autre variante ou terminologie similaire. Bien que la Société considère que ses projections sont basées sur des hypothèses et attentes raisonnables de sa Direction Générale, ces déclarations prospectives peuvent être remises en cause par un certain nombre d’aléas et d’incertitudes connus ou inconnus, ce qui pourrait donner lieu à des résultats substantiellement différents de ceux décrits, induits ou anticipés dans lesdites déclarations prospectives. Ces aléas et incertitudes comprennent, parmi d’autres, les incertitudes inhérentes à la recherche et développement, y compris dans le domaine des biomarqueurs, au progrès et aux résultats des essais cliniques prévus et en cours, aux examens et autorisations d’autorités réglementaires concernant ses candidats-médicaments et solutions diagnostiques, à la fluctuation des devises, à la capacité de la Société à continuer à lever des fonds pour son développement, ainsi qu’à ceux développés au Chapitre 2 « Facteurs de risque et contrôle interne » du Document d’Enregistrement Universel 2019 de la Société déposé auprès de l’Autorité des marchés financiers (« AMF ») le 27 mai 2020 sous le numéro D.20-0503, ainsi qu’à la section 2 « Facteurs de risque » de de l’Amendement au Document d’Enregistrement Universel déposé auprès de l’AMF le 22 décembre 2020 sous le numéro D.20-0503-A01, disponibles sur les sites Internet de GENFIT (www.genfit.fr) et de l’AMF (www.amf-france.org) et à ceux développés dans les documents publics et rapports déposés auprès de la Securities and Exchange Commissions (« SEC ») américaine, y compris le Rapport Annuel Form 20-F déposé auprès de la SEC le 27 mai 2020. De plus, même si les résultats, la performance, la situation financière et la liquidité de la Société et le développement du secteur industriel dans lequel elle évolue sont en ligne avec de telles déclarations prospectives, elles ne sauraient être prédictives de résultats ou de développements dans le futur. Ces déclarations prospectives ne sont valables qu’à la date de publication de ce document. Sous réserve de la réglementation applicable, la Société ne prend aucun engagement de mise à jour ou de révision des informations contenues dans ce communiqué, que ce soit en raison de nouvelles informations, d’évènements futurs ou autres. CONTACT GENFIT Naomi EICHENBAUM – Relations Investisseurs | Tel : +1 (617) 714 5252 | investors@genfit.com Hélène LAVIN – GENFIT | Tel : 03 20 16 40 00 | helene.lavin@genfit.com Relations Presse - ULYSSE COMMUNICATION - Bruno ARABIAN | Tel : 06 87 88 47 26 | barabian@ulysse-communication.com 1 Hors frais liés à l’opération 2 Données non auditées établies selon les normes IFRS3 Chiffre d’affaires reconnu en application de la norme IFRS 154 Hors frais liés à l’opération GENFIT | 885 Avenue Eugène Avinée, 59120 Loos - FRANCE | +333 2016 4000 | www.genfit.com Pièce jointe 2021.02.26 - GENFIT CP - Position de Trésorerie au 31 décembre 2020

  • Globe Newswire

    GENFIT: new market research data highlight potential of elafibranor in PBC

    Insights from Pr. Sven Francque and Dr. Kris V. Kowdley on PBC, a chronic, cholestatic, autoimmune liver disease with high unmet medical needs despite available therapiesPeak sales for elafibranor as potential second line treatment for PBC estimated at $515 million in 2035 on a total market of $1.5bn in 2035 according to research commissioned by GENFIT from IQVIA Lille, France; Cambridge, MA; February 22, 2021 - GENFIT (Nasdaq and Euronext: GNFT), a late-stage biopharmaceutical company dedicated to improving the lives of patients with metabolic and liver diseases, today discusses the highlights from its KOL Analyst Event on Primary Biliary Cholangitis (PBC), the therapeutic landscape and commercial opportunity. The event focused on GENFIT’s new priority program. It provided KOL insights on PBC, details on GENFIT’s Phase 2 data recently published in the Journal of Hepatology, highlights on the ongoing ELATIVE™ Phase 3 clinical trial, and projections on elafibranor’s commercial opportunity. The PBC KOL analyst event replay can be accessed here. Pascal Prigent, CEO of GENFIT, commented: “GENFIT has completed its restructuring efforts and we are now implementing our new corporate strategy announced last fall. R&D is focused on several key priority programs that we will present in more detail this summer. We have significantly reduced our cash burn from operations with a goal to reach roughly 50% of our 2020 cash burn in 2022, and with a 40% workforce reduction, we are a leaner organization with a specialty focus. We have renegotiated our debt which is less than half of what it was and is rescheduled to be due at the end of 2025. We are now fully committed to the successful execution of our PBC program and in particular our ELATIVE™ Phase 3 trial which began 5 months ago. In this context we felt it was useful to have an in-depth presentation of this exciting opportunity.” What is PBC? PBC is a severe chronic, cholestatic, autoimmune liver disease causing injury to the intrahepatic bile ducts, resulting in liver injury and cirrhosis. There is no known cure for PBC, and at present there are only two approved treatment options for first or second line treatment. The disease symptoms – pruritus and fatigue – are not addressed by existing therapies and ~40% of patients are non or partial responders to first line therapy1, resulting in a highly underserved patient population. Pr. Sven Francque, Chairman of the Department of Gastroenterology and Hepatology of the University Hospital Antwerp, commented: “PBC is a serious liver disease, and unfortunately, we still see patients who inevitably progress to later stages, developing decompensated cirrhosis and requiring a liver transplant, confirming the significant need for novel PBC therapies. Clinical studies have demonstrated that PPAR alpha and PPAR delta agonists have positive effects on PBC patients. Elafibranor activates both PPAR alpha and delta simultaneously, therefore we can hypothesize a synergistic effect to potentially enhance the positive outcome in PBC patients.” Dr. Kris V. Kowdley, Director, Liver Institute Northwest, Clinical Professor Elson S. Floyd College of Medicine, Washington State University added: “PBC can be a debilitating disease with a profound impact on a patient’s quality of life. As one of my patients explained during the call, the most difficult symptom remains pruritus, a severe itching causing extreme discomfort which is experienced as a real burden. Finding a treatment that could halt the progression of the disease and concurrently improve symptoms would address many of the existing challenges faced by patients with PBC.” PBC Commercial Opportunity PBC represents a significant market opportunity for GENFIT as the disease has a clear regulatory pathway and is well understood by payors and KOLs. IQVIA, a recognized leader in research and consulting services for the pharmaceutical industry, was commissioned by GENFIT to conduct three comprehensive market research studies evaluating the potential market opportunity, should it be granted regulatory approval, of elafibranor as a second line treatment. The total PBC market is estimated to reach $1.5 billion annually in 2035, and elafibranor, if approved, could achieve $515 million in peak year revenue, as second line treatment for patients with PBC that cannot benefit from the first line therapy. Julien Perrier, VP Global Account at IQVIA, commented: “It is estimated that 90,000 patients could be treated with elafibranor by 2030, if approved. Our payer and KOL research, based on a robust methodology involving 28 KOLs, 240 healthcare professionals and 15 US and EU payors, showed that elafibranor is considered to have the potential for a strongly differentiated profile in terms of safety, efficacy, and improvement on pruritus. Our research model, based on conservative assumptions, shows that elafibranor’s profile could potentially justify a market penetration of ~32% in the United States and ~22% in the EU in 2035.” Upcoming Investor Events Following this PBC KOL event, GENFIT will be taking part in the SVB Leerink 10th Annual Global Healthcare Conference from Feb 22 to 26, with a fireside chat scheduled on February 24 from 10:40 am EST to 11:10 am EST.GENFIT will also be taking part in the H.C. Wainwright Global Life Sciences Conference on March 9 and 10, with a recorded fireside chat to be made available on March 9. ABOUT GENFIT GENFIT is a late-stage biopharmaceutical company dedicated to improving the lives of patients with cholestatic and metabolic chronic liver diseases. GENFIT is a pioneer in the field of nuclear receptor-based drug discovery, with a rich history and strong scientific heritage spanning more than two decades. GENFIT is currently enrolling in ELATIVE™, a Phase 3 clinical trial evaluating elafibranor in patients with Primary Biliary Cholangitis (PBC). Elafibranor is an investigational compound that has not been reviewed and has not received approval by any regulatory authority. As part of GENFIT’s comprehensive approach to clinical management of patients with liver disease, the Company is also developing NIS4™, a new, non-invasive blood-based diagnostic technology which could enable easier identification of patients with at-risk NASH. NIS4™ technology has been licensed to LabCorp in the U.S. and Canada for the development and commercialization of a blood-based molecular diagnostic test powered by NIS4™ technology. GENFIT has facilities in Lille and Paris, France, and Cambridge, MA, USA. GENFIT is a publicly traded company listed on the Nasdaq Global Select Market and on compartment B of Euronext’s regulated market in Paris (Nasdaq and Euronext: GNFT). www.genfit.com FORWARD LOOKING STATEMENTS This press release contains certain forward-looking statements with respect to GENFIT, including those within the meaning of the Private Securities Litigation Reform Act of 1995, with respect to GENFIT, including statements regarding our expected future performance, business prospects, financial perspective, corporate strategy, events and plans, including timing ability to meet clinical, regulatory and commercial milestones and timelines in our PBC program, expectations for disease prevalence, growth and size of the PBC market, including GENFIT’s potential market share and revenues. The use of certain words, including “consider”, “contemplate”, “think”, “aim”, “expect”, “understand”, “should”, “aspire”, “estimate”, “believe”, “wish”, “may”, “could”, “allow”, “seek”, “encourage” or “have confidence” or (as the case may be) the negative forms of such terms or any other variant of such terms or other terms similar to them in meaning is intended to identify forward-looking statements. Although the Company believes its projections are based on reasonable expectations and assumptions of the Company’s management, these forward-looking statements are subject to numerous known and unknown risks and uncertainties, which could cause actual results to differ materially from those expressed in, or implied or projected by, the forward-looking statements. These risks and uncertainties include, among other things, the uncertainties inherent in research and development, including in relation to safety, biomarkers, progression of, and results from, its ongoing and planned clinical trials, review and approvals by regulatory authorities of its drug and diagnostic candidates, exchange rate fluctuations and the Company’s continued ability to raise capital to fund its development, as well as those risks and uncertainties discussed or identified in the Company’s public filings with the AMF, including those listed in Chapter 2 “Main Risks and Uncertainties” of the Company’s 2019 Universal Registration Document filed with the AMF on 27 May 2020 under n° D.20-0503 and in Section 2 “Risk Factors” of the Company’s Amendment to the Universal Registration Document filed with the AMF on 22 December 2020 under n° D.20-0503-A01, which are available on the Company’s website (www.genfit.com) and on the website of the AMF (www.amf-france.org) and public filings and reports filed with the U.S. Securities and Exchange Commission (“SEC”) including the Company’s 2019 Annual Report on Form 20-F filed with the SEC on May 27, 2020. In addition, even if the Company’s results, performance, financial condition and liquidity, and the development of the industry in which it operates are consistent with such forward-looking statements, they may not be predictive of results or developments in future periods. These forward-looking statements speak only as of the date of publication of this document. Other than as required by applicable law, the Company does not undertake any obligation to update or revise any forward-looking information or statements, whether as a result of new information, future events or otherwise. CONTACT GENFIT | Investors Naomi EICHENBAUM – Investor Relations | Tel: +1 (617) 714 5252 | investors@genfit.com PRESS RELATIONS | Media Hélène LAVIN – Press relations | Tel: +333 2016 4000 | helene.lavin@genfit.com GENFIT | 885 Avenue Eugène Avinée, 59120 Loos - FRANCE | +333 2016 4000 | www.genfit.com 1 Lindor, K. D., Bowlus, C. L., Boyer, J., Levy, C., & Mayo, M. (2018). Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases. Hepatology, 394‑419. https://doi.org/10.1002/hep.30145 Attachment GENFIT: new market research data highlight potential of elafibranor in PBC